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Children receiving CRWP showed a significant increase in glutathione levels and selective improvements in adaptive behavior and socialization domains ( Glutathione is able to improve the antioxidative system decreasing the oxidative damage and the neuroinflammation caused to the neurons (Ghanizadeh et al., 2012)

Moreover, GLP-1R cascade also has interactions to regulatory proteins involved in the insulin receptor cascades such as the insulin receptor substrates (IRS) and the PI3K involved in the positive regulation for survival, metabolism and proliferation of beta pancreatic cells as well as apical glucose transport in peripheral tissues

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10.1074/jbc.M410818200