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206 Combined administration of shikonin and cisplatin increases Fe 2+ , ROS, and lipid peroxidation (LPO) levels and downregulates GPX4 in ovarian cancer cells, reducing cisplatin resistance by inducing ferroptosis
Using next-generation RNA-seq sequencing technology, they confirmed that GHK-Cu modulates the expression of 4,231 genes , of which 2,861 are upregulated and 1,370 are downregulated
There are also no reported withdrawal symptoms
GHK-Cu is in a category of its own compared to other peptides like BPC-157 or Semax, it does not address inflammation or cognitive function in the same way
On the other hand, a diet high in processed foods can increase oxidative stress and inflammation, which may deplete your glutathione stores and make it harder for your body to protect itself
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