Front Oncol (2013) 3:123
Tendon collagen turns over slowly, the blood supply to tendons is inherently limited, and the mechanical demands on tendons mean they need to rebuild strength progressively rather than all at once
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For example, in tissues and cells, the free radical oxidation of linoleic acid produces racemic mixtures of 13-hydroxy-9 Z ,11 E -octadecadienoic acid, 13-hydroxy-9 E ,11 E -octadecadienoic acid, 9-hydroxy-10 E ,12- E -octadecadienoic acid (9-EE-HODE), and 11-hydroxy-9 Z ,12- Z -octadecadienoic acid as well as 4-Hydroxynonenal while singlet oxygen attacks linoleic acid to produce (presumed but not yet proven to be racemic mixtures of) 13-hydroxy-9 Z ,11 E -octadecadienoic acid, 9-hydroxy-10 E ,12- Z -octadecadienoic acid, 10-hydroxy-8 E ,12 Z -octadecadienoic acid, and 12-hydroxy-9 Z -13- E -octadecadienoic (see 13-Hydroxyoctadecadienoic acid and 9-Hydroxyoctadecadienoic acid)