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This inference is hypothesis-generating, not confirmatory

If you have experienced this, you understand why it is distressing

Nature 464 , 783U163 (2010)

The claims are not supportable by this kind of study, he said

Concomitantly with the development of resistance the up-regulation of a hydrogen-peroxide inducible GST was observed that might contribute to the elimination of cytotoxic reactive metabolites containing an electrophilic moiety (Shibu et al., 2012)