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Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1 , are co-expressed in a subset of taste receptor cells
The peptide incorporates a C20 fatty diacid moiety via a Glu-Glu linker enabling reversible albumin binding and an extended pharmacokinetic profile compatible with once-weekly dosing
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Because the incisions are smaller, they do not need to be closed by sutures
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