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Important safety considerations for tirzepatide include a boxed warning for risk of thyroid C-cell tumors (including medullary thyroid carcinoma), and warnings regarding pancreatitis, gallbladder disease, acute kidney injury with dehydration, and increased hypoglycemia risk when used with insulin or sulfonylureas

GLP-1 medicines are prescription drugs and should only be started after evaluation by a qualified doctor.

Ask whether your provider has a plan for long-term access, and if theyll help transition you to an FDA-approved version if needed, Miller says