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In another, a lifespan trial in Swiss-derived SHR mice (1 g/mouse per month) reported no changes in food intake or body weight, while chromosomal aberrations decreased and maximum lifespan increased [7]
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And its a history with its share of ignominy: In the mid-1990s, a drug that combined fenfluramine and phentermine, known as fen-phen, exploded in popularity after a single, 121-patient study showed it was effective for weight loss
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