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Preliminary evidence from the first published case report on semaglutide treatment for MC4R -deficient obesity [76] suggested a potential therapeutic effect
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These findings align with literature proposing multiple pathways through which semaglutide may act, mitigating vascular stiffening, adverse lipid profiles, inflammation, and endothelial dysfunction, alongside effects on glycemic control, insulin resistance, and weight loss [1, 4]
Other forms, like Ozempic and Rybelsus, also contain semaglutide but they are more commonly used for blood sugar support and are not used in the same way