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GLP-1 plays a central role in regulating appetite, blood sugar, and digestion, but in many people particularly those with obesity or metabolic dysfunction this hormonal signaling is impaired or insufficient to maintain a healthy weight

Prescribing information (Eli Lilly, 2025)

Venner emphasizes that naturally produced GLP-1 and GLP-1 drugs like Ozempic aren't the same

Conventional anti-obesity medications are limited to short-term use and have adverse effects, which have contributed to the rise of GLP-1 RAs, e.g., liraglutide, semaglutide, dulaglutide