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Phenotypic Screening Deconvolution After a phenotypic screen identifies active compounds, metabolic fingerprinting provides the first mechanistic triage layer separating compounds that act through energy metabolism, membrane disruption, nucleotide biosynthesis, or signalling pathway inhibition without requiring individual target binding assays

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Biomarkers from blood, follicular fluid, or endometrial biopsy can guide which peptide motifs to use, what dose, and what delivery route, such as vaginal gel, intrauterine device, or localized injection

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LDL, lowdensity lipoprotein