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Retatrutide looks more mechanistically aggressive: CagriSema looks more like an incremental combination of two better-understood pathways

A 2021 randomized controlled trial published in Diabetes Care (N=105) compared dulaglutide 1.5 mg weekly against glimepiride over 24 weeks in adults with type 2 diabetes and found that dulaglutide significantly reduced plasma malondialdehyde (a lipid peroxidation marker) and raised superoxide dismutase activity

It is known to influence growth factors and enhance angiogenesis, which supports tissue regeneration

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