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These included nausea, vomiting, diarrhea, and constipation, and were generally dose-dependent and most pronounced in the first weeks of dose escalation
Crucially, a medic such as Dr
[1] Because its multiple ion-channel and neurotransmitter actions dampen pathologic cortical excitability, topiramate received United States marketing clearance in 1996 for monotherapy or adjunctive control of partial-onset and primary generalized tonic-clonic seizures
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