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Prescription GLP-1 treatments have been tested in large, long-running clinical trials involving thousands of participants: Semaglutide 2.4 mg (Wegovy) participants lost an average of around 1521% of their body weight over 6872 weeks in the STEP trials Tirzepatide (Mounjaro) the SURMOUNT trials showed average weight loss of 2025% of starting body weight at the highest dose over 72 weeks These results come from rigorously controlled studies with safety monitoring, dose titration, and long-term follow-up

When used to treat joint-related pain, it can promote regeneration in the joint and accelerate healing

Thermal Allodynia Pain caused by mild changes in temperature