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Glutathiones key role in the aging process has been put to the test by Danish researchers who examined the glutathione levels of centenarians

10.1021/acsomega.2c01779 135 EllisG.FangE.MaheshwariM.RoltschE.HolcombL.ZimmerD.et al (2010)

They emphasized that the use of metformin can prevent the absorption of B12, resulting in a deficiency that can have negative clinical consequences, such as anemia and neurological problems