Kraft M, Kraft K, Grtner S, Mayerle J, Simon P, Weber E, Schtte K, Stieler J, Koula-Jenik H, Holzhauer P, Grber U, Engel G, Mller C, Feng YS, Aghdassi A, Nitsche C, Malfertheiner P, Patrzyk M, Kohlmann T, Lerch MM
Long-term success: The program encourages the development of healthy habits that can be maintained long after treatment ends
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228,229,230 Inhibiting xCT The search for strategies and drugs aimed at inducing oxidative stress has revealed xCT to be a suitable targetincreased glutamate efflux through this antiporter is an important process for cells to generate sufficient glutathione to cope with high intracellular ROS levels