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Some protocols incorporate topical application to specific areas of concern alongside injectable administration for localized plus systemic benefits

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These fluid markers can be sampled longitudinally with minimal invasiveness, and combining them with TSPO-PET or other microglial/astrocytic imaging readouts yields a multimodal profile that better characterizes active neuroinflammatory states and may inform anti-inflammatory or disease-modifying treatment strategies (145)

Have you had a homocysteine blood test and a methylmalonic acid - MMA - that would show whether you were low at cellular level