Ethanol metabolism, CYP2E1 induction, compromised antioxidant defenses, mitochondrial injury, activation of Kupffer and stellate cells, hypoxia, and iron overload can all contribute to the alcohol-induced oxidative environment
Stress, cigarettes, caffeine, alcohol poor diet, toxins, over-the-counter medications, aging and a lot of the mundane things in our life deplete the body of this important antioxidant
Glutathione is found in every cell of the body
The percentage of 5-mC detected in DNA samples using a 5-mC DNA ELISA Kit strongly correlates with mass spectrometry (MS) data demonstrating 5-mC found in the same gDNA sample
A byproduct of this metabolically intensive process is creation of free radicals