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Similar to the longitudinal muscle layer, cumulative application of BTCH (10 8 to 10 3 M) to jejunal circular muscle strips from non-diabetic patients induced a concentration-dependent increase in contraction force (Figure 5A)

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PMID: 10828840 Published Research Highlights Foundational Pharmacology 1998 First selective GHSR-1a agonist characterization Raun, Hansen, Johansen, and colleagues at Novo Nordisk reported that ipamorelin stimulated pulsatile GH secretion in rats, pigs, and dogs with selectivity over ACTH/cortisol release not seen with GHRP-6 or GHRP-2 at equivalent GH-effective doses

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