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The ability to maintain or restore optimal glutathione status represents a fundamental strategy for promoting healthspan and preventing oxidative stress-related pathological processes

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Therefore, we focused on the effect of semaglutide, a long-acting GLP1R agonist, on cardiac hypertrophy induced by pressure overload in this study

Semaglutide 2.4 mg, a glucagon-like peptide-1 receptor agonist, is a once-weekly injectable pharmacological treatment, indicated in combination with diet and exercise, for reducing body weight in adults with obesity or overweight and at least one ORC [8]