Mild diarrhea, upset stomach, nausea, a feeling of pain and a warm sensation at the site of the injection, a feeling, or a sense, of being swollen over the entire body, flushing, headache, skin rashes, and joint pain
GLP-1 signaling also antagonizes voltage-dependent K + (Kv) channels via cAMP/PKA-dependent pathway in beta cells, which prevents beta-cell repolarization by reducing Kv currents
How many manufacturers plan to make a generic version
But the trough is arguably more important for sustained results
While some have faded into obscurity, others have stood the test of time due to their proven benefits and effectiveness