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SIRT1 and AMPK share several roles, including reacting to nutritional status and stress, initiating mitochondrial biogenesis, regulating the activity of important transcriptional regulators such as PGC-1, and managing glucose homeostasis (Lan et al., 2008)
Exercise-induced factors such as irisin, IL-6, BDNF, and FGF21 collectively modulate inflammation, attenuate oxidative stress, and enhance neurotrophic and mitochondrial support, thereby preventing hyperglycemia-induced neurodegeneration
Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite
Ueda M et al
10.1002/ptr.2572 100 TruongV
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