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Sulforaphane protects against 6-hydroxydopamine-induced cytotoxicity by increasing expression of heme oxygenase-1 in a PI3K/Akt-dependent manner

Mechanisms of photoreceptor death and survival in mammalian retina

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High glucose-induced hyperosmolarity contributes to COX-2 expression and angiogenesis: implications for diabetic retinopathy

Furthermore, studies have shown that mitochondrial-targeted nanodrugs enhance the sensitivity of cancer cells to chemotherapy drugs by intervening in mitochondrial function, further emphasizing the emerging therapeutic strategy of reversing drug resistance through mitochondrial metabolic reprogramming [146]