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GLP-1 RAs [glucagon-like peptide-1 receptor agonists] have been around more than 15 years for diabetes, says Brian Johnson, MD and Regional Vice President of Clinical Leadership at Marathon Health
Why You Need Strength Training on GLP-1 Medications GLP-1 medications like Ozempic and Wegovy are powerful tools for weight lossbut they can also decrease appetite, reduce protein intake, and lead to unwanted muscle loss
Similar results were observed in a separate trial specifically designed to test the effect of retatrutide therapy on knee pain
Key Regulatory Points: Not FDA-approved for any medical indication Cannot legally be sold as a drug, food, or dietary supplement for human consumption Legally sold as a "research chemical" not intended for human use Compounding pharmacy restrictions were significantly tightened in late 2024 Sports / WADA CJC-1295 is explicitly prohibited by the World Anti-Doping Agency (WADA)
