NIBSC CJD Resource Centre

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For long-acting agents such as semaglutide, clinicians generally recommend stopping therapy at least two months before attempting pregnancy due to the extended half-life
In their marketing, telehealth companies claim that compounded GLP-1s in small doses starting lower than FDA-approved doses from Novo Nordisk and Eli Lilly can reduce metabolic risk, lower inflammatory markers, and even lower the risk of cognitive decline
These trials, expected to conclude by February 2026, will provide critical data on sustained weight loss, cardiovascular outcomes, and kidney function