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This emerging practice is gaining interest for its potential role in metabolic optimization, weight maintenance, and managing side effects

It increases the dose at a moderate rate faster than a conservative plan, but still gradual enough to manage side effects

[9] It shows promise for HFpEF and cardiovascular protection , reducing inflammation, and improving heart and vascular health

These anecdotal reports, which constitute low-level evidence, have gained considerable attention on social media platforms and in patient communities, prompting scientific investigation into whether these observations represent a genuine pharmacologic effect or coincidental behavioral changes associated with improved metabolic health and weight loss

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