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A significant fraction of the heme moeity may be converted to metabolites other than bilirubin, such as mesobilifuscins, that are excreted in the bile/feces and urine (70)
Creating a written action plan during stable periods provides a roadmap for crisis times
The energy of the resulting structure was minimized utilizing AMBER14:EHT forcefield in MOE 72,73 with all the settings set default until the RMS gradient reached 0.001 kcal/mol/ 2
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