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They promote insulin secretion only when blood sugar is high, so they are said to have a low risk of hypoglycemia and relatively high safety

2024;108(7):e1218

Alveolar epithelial cells appear to be remarkably tolerant to oxygen deprivation as they are able to maintain adequate cellular ATP content during prolonged hypoxic exposure [12] and hence considered as an elegant gatekeeper between environmental hypoxia and physical performance at high altitude [8,13]

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They talk about the challenges they faced with everyday activities, the impact on their self-esteem, and the constant struggle to manage their body mass index (BMI)