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The FDA's staff reviewers had last month said there is little evidence to support the safety and effectiveness of these peptides for their intended uses and flagged a lack of adequate human clinical trials, in contrast to Kennedy's public support

Since CagriSema already contains semaglutide 2.4 mg, transitioning from standalone semaglutide to CagriSema would theoretically be simpler, though clinical guidance on this transition is limited

K.Erdjument-BromageH.TempstP.et al

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