Glutathione plays a key role in Phase II detoxification by binding to these reactive compounds through conjugation, transforming them into water-soluble substances that your body can safely eliminate
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Glutathione deficiency and oxidative stress in aging: metabolic mechanism and targeted intervention
SAG has the ability to penetrate the mitochondrial membrane, helping to maintain its integrity and function
However, this in vitro observation may not be valid for the brain in vivo , and in glutamate-dehydrogenase knock-out mice glutamate oxidation, determined in astrocyte cultures is reduced, but absolutely not abolished (Frigerio et al., 2012)