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However, more studies and trials are required to adjust the optimum dosing of ALA for the treatment of patients
Results continue building with additional cycles
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The source in this case may be pyruvate from glycolysis, beta-oxidation of fatty acids, or proline (or possibly glutamine), which is converted in the mitochondria to glutamate and alpha-ketoglutarate, which may be converted in one direction to isocitrate and in the other to malate, thus serving as a source for NADPH formation
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