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1 (5th ed.)
Four-week administration of AVE3085 upregulates eNOS mRNA and protein levels, enhances eNOS phosphorylation and decreases nitrotyrosine formation, leading to improved endothelium-dependent vasorelaxation in hypertensive animals (Yang et al., 2011)
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Another similar drug that has gained popularity is tirzepatide (Mounjaro), which is a combination GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptor agonist
The conversion chart helps ensure dosing equivalence during switches
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