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This process not only slows down hypoxia-induced endothelial cell senescence but also aids in restoring damaged endothelial cell function, offering new insights and potential intervention strategies for related diseases
In summary, the study demonstrates that FOXO4-DRI effectively eliminates senescent Leydig cells, improves the testicular microenvironment, and alleviates age-related testosterone secretion insufficiency, highlighting its therapeutic potential for male late-onset hypogonadism [1]
