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Research has shown protective effects against age-related changes in retinal tissue and potential benefits for neurodegenerative conditions

TLRs can be localized either on the cell surface (TLR-1, -2, -4, -5, -6, -10) or in the endosome compartment (TLR-3, -7, -8, -9

The GLP-1 receptor (GLP-1R) is expressed in pancreatic beta cells, the central nervous system, and the gastrointestinal tract

Discussion In this study, we have developed a novel AML-specific drug-delivery system, TLR2 pep conjugated oridonin-liposome

In A1-42-induced HT-22 cells, ERD (2, 4, and 8 M) significantly enhanced cell survival, reduced Tau hyperphosphorylation and neurotoxicity, and decreased lipid ROS and iron levels, highlighting its neuroprotective potential (Li L