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Several promising studies in animal models demonstrated a marked improvement in cognition
Patients should not substitute oral and injectable semaglutide without clinical guidance
Semaglutide can cause mild or serious side effects
2022;8:e12268
Conducting rigorous studies like those that established the benefits of injectable GLP-1 RAs such as tirzepatide, semaglutide, dulaglutide, and liraglutide on CKD, MASH, and cardiovascular outcomes will be crucial in determining the full clinical utility of these novel agents
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