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However, a promising active ingredient in clinical trials is not automatically an approved, available, or individually suitable medication

10.1016/j.bbabio.2009.06.004 20 DescoeurJ.PereiraV.PizzoccaroA.FrancoisA.LingB.MaffreV.et al (2011)

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Policymakers and regulators should demand this or keep the shortage in place to meet the very real demand at these lower pricesthe same prices at which these medications are available in the rest of the world

Uptake in this population remains low and many older patients do not initiate the therapy after an event