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After 13 weeks of treatment, patients taking Duloxetine 60-120 mg daily had a significantly greater pain reduction compared to placebo
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The involvement of medicinal chemists will also help delineate the impacts of different structural changes, such as different terminal linkages with GSH ( C -terminal, S -terminal, and N -terminal), on binding selectivity and efficiency, and establish structure-activity relationships (SAR) for the development of glutathione transporter-based brain targeting ligands
Nutrients 2022;14(19)
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