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Fatigue can occur both as a direct side effect and indirectly through several mechanisms related to how these medications work
However, the retatrutide trials were designed primarily to measure outcomes at scheduled study visits
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A landmark analysis was used to evaluate events occurring after week 20, acknowledging that a proportion of cardiovascular events occurred before substantial weight or waist changes had developed, which may complicate interpretation of mediation analyses
Yang T, Xu Z, Liu W, Xu B, Deng Y (2020a) Oxidative stress accelerates synaptic glutamate dyshomeostasis and NMDARs disorder during methylmercury-induced neuronal apoptosis in rat cerebral cortex
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