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By week eight to twelve, most people report minimal ongoing side effects

Lancet 387(10019):679690 Newsome PN, Buchholtz K, Cusi K, Linder M, Okanoue T, Ratziu V, Sanyal AJ, Sejling A-S, Harrison SA (2021) A placebo-controlled trial of subcutaneous semaglutide in nonalcoholic steatohepatitis

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A smaller dose may likely only offer smaller benefits, Zimmermann adds