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Anyone experiencing symptoms of deficiency particularly neurological symptoms should seek medical review promptly rather than relying solely on self-supplementation

While research has shown that histamine itself helps mast cells release histamine, this study considers for the first time that certain mechanisms might also inhibit histamine release and that there may be more going on behind the disease than previously thought

doi: 10.1016/j.biopha.2021.111274 75 XuZTianNLiSLiKGuoHZhangHet al

Longer term For longer protocols, review metabolic, kidney, liver, and cardiovascular trends every 3-6 months with a clinician

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