Classic manifestations include hypermobile joints (joints that move excessively and dislocate easily), skin hyperextensibility (unusually stretchy, fragile skin), and tissue fragility such as easy bruising and poor wound healing
What this means clinically is that GHK-Cu works on multiple fronts simultaneously

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For topical users , medical professionals have conveyed to us that GHK-Cu often yields results along the following timeline: First two weeks: Users may notice better skin hydration, reduced redness or irritation, and smoother skin
It remains available by prescription in North America, but the trend in dermatology is moving toward safer long-term alternatives