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The reticulophagy restoration mediated by glutathione s-transferase kappa 1-reticulophagy regulator 1 ameliorated DKD by suppressing tubular apoptosis (37)
Meanwhile, PEDF induces a protective transcriptional profile in the hippocampus, liver and kidney of aged mice, improving cognitive function as well as liver and kidney integrity, suggesting that maintaining or supplementing PEDF levels in the elderly may have therapeutic implications for age-related diseases and chronic disorders of these tissues (46)
S.Alves-FilhoJ
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Vomiting, nausea, diarrhea, constipation and other gastrointestinal issues are common with GLP-1s
