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In a recent study, exogenous DPP4 or upregulation of DPP4 in synovial fibroblasts was found to reduce the release of proinflammatory cytokines such as IL-6, IL-3, and IL-1
The Phase 2 trial data showed consistent appetite suppression and continued weight maintenance through 48 weeks, with no evidence of the medication losing effectiveness over time
Jardiance has also demonstrated reduced risk of the composite endpoint of cardiovascular death or rate of hospitalization for heart failure in patients with congestive heart failure, and slowed decline in kidney function
2014 Oct 31;289(44):30303-30317
Why is this study important
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