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NAC is best known in medicine for its use as an antidote to paracetamol (acetaminophen) poisoning, but its benefits extend far beyond this application

Whether declining MOTS-c is a cause or consequence of this deterioration is still being resolved, but the correlation is striking enough that some researchers have proposed plasma MOTS-c as a biomarker of mitochondrial vitality and metabolic age

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As for adverse events, a similar percentage of participants across the treatment groups experienced the most common side effect of gastrointestinal upset [2]