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Reported side effects of corticosteroids include: Hydroelectrolytic disorders: sodium retention, potassium loss, hypokalemic alkalosis, fluid retention, congestive heart failure in susceptible patients, hypertension Musculoskeletal: muscle weakness, myopathy, loss of muscle mass, aggravation of myasthenic symptoms in myasthenia gravis, osteoporosis, vertebral compression fractures, aseptic necrosis of the head of the femur and humerus, pathologic fracture of long bones, tendon rupture Dermatological: impaired wound healing, atrophy and thinning of the skin, fragile skin, petechiae and ecchymoses, facial erythema, increased sweating, suppression of reactions to skin tests, allergic dermatitis, urticaria, and angioedema
Researchers might accept a degree of variability for the sake of convenience
Individual factors including genetics, baseline health, severity of issues being addressed, lifestyle factors, and consistency of use all affect whether any individual experiences changes, and many users experience no noticeable effects
[PMID: 18272931] PubMed record related to this compound for laboratory literature review