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Each point represents the mean of at least 2 independent analyses (technical replicates) on hepatocytes isolated from a single mouse (biological replicates)
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The alteration in membrane structure over time can cause the disruption of cellular calcium homeostasis and increases in intracellular calcium concentrations, which can ultimately bring about cytotoxicity (Atchison and Hare, 1994
C., & Ribeiro-Barros, A
