does sulforaphane increase glutathione reactivates cellular antioxidant defense by inducing Nrf2/ARE/Prdx6 activity during aging and oxidative stress Sulforaphane's Multifaceted Potential: From Neuroprotection

Gut microbiota composition changes due to metformin Metformin is increasingly recognised for its role in the gut, including modifications to the microbiome which might account for some of the drugs therapeutic efficacy and side effects (McCreight et al., 2016

In cautious research discussion, no the emphasis is on titrating each compound independently and slowly, never pushing both to maximum simultaneously, because the combination has never been tested for safety in humans

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