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What does matter is gastric motility: delayed emptying (which occurs postprandially and during evening hours as part of parasympathetic dominance) can hold the compound in the stomach longer, theoretically extending the time to peak concentration without altering total absorption

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It is not a replacement for these foundationsbut rather a potential complement to them

Dawes P, Cruickshanks KJ, Marsden A, Moore DR, Munro KJ