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Under conditions leading to hypovolemia the extracellular fluid volume needs to be tightly regulated in order to ensure proper regulation of blood pressure and resultant organ perfusion

If light or noise is an issue, consider using blackout curtains and a white noise machine to block out disturbances

(2) R T Dorr, R Lines, N Levine, C Brooks, et al (1996) Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study Life Sciences, 1996, Volume 58 (Issue 20), Pages 1777-84

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PTSD+MDD ( n = 7) participants had 30% higher ( p = 0.015) MPO concentrations compared to PTSD only participants ( n = 18)