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Retatrutide's Phase 2 trial data (Jastreboff et al., NEJM 2023) identified a side-effect profile broadly consistent with other incretin-based therapies: Gastrointestinal : Nausea, vomiting, diarrhoea, and constipation were the most commonly reported adverse effects, particularly during dose escalation
Is B12 safe
Additionally, we encourage you to adhere to any lifestyle modifications we suggest to ensure optimal absorption and maintenance of Vitamin B12 levels
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