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A peptide can be 99 percent pure and still have no meaningful biological activity if the sequence contains racemized amino acids (L to D inversion during synthesis) or has the correct primary sequence but incorrect folding context
PFIC3 PFIC3 is caused by variants in the ABCB4 gene, which encodes multidrug-resistance protein 3 (MDR3/ABCB4)
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Obese and lean mice were given either saline, AOD9604, or hGH through an osmotic pump over the course of 14 days
tirzepatide is a dual GIP/GLP-1 incretin agonist a contrast, not an equivalence
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